Hypophosphatasia is a systemic, inherited metabolic bone disease characterized by low alkaline phosphatase activity that is commonly misdiagnosed due to its similarities with other musculoskeletal diseases.
In this program, we’ll cover: • The role of ALP in bone mineralization and maintaining calcium and phosphate homeostasis • Hypophosphatasia, a metabolic disease of the bones, and key signs and symptoms to evaluate for its accurate diagnosis • Medical conditions that have overlapping presentations with HPP, including hypothetical patient case studies